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Biological Potency

Meaning

Biological potency is a quantitative measure of the magnitude of a therapeutic agent’s effect on a living system, specifically the dose required to produce a defined therapeutic response. In endocrinology, it refers to the efficacy of a hormone or hormone analog to elicit a cellular response upon receptor binding. This metric is fundamental for clinical dosing, ensuring that the lowest effective concentration is used to achieve the desired physiologic outcome while minimizing off-target effects.