A broad classification encompassing hormones, neurotransmitters, and cytokines—signaling molecules that transmit information between cells, tissues, and organs to coordinate physiological processes. These molecules are essential for maintaining homeostasis and orchestrating complex functions like metabolism, reproduction, and immune response. They operate via receptor binding, ensuring high specificity in communication across the body.
Origin
This term is a descriptive, functional designation rooted in the foundational principles of cell biology and endocrinology. The concept of a chemical ‘messenger’ derives from the molecules’ primary role of conveying a signal from a source cell to a distant target cell. The understanding of these messengers forms the basis of all physiological communication.
Mechanism
These chemical agents are secreted in response to stimuli and travel through the circulatory system or synaptic clefts to reach target cells possessing specific receptors. Binding to these receptors triggers a cascade of intracellular events, ultimately altering cellular function, gene expression, or protein synthesis. The precision and speed of this communication are vital for adaptive physiological responses and maintaining systemic equilibrium.
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