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Biological Membrane Navigation

Meaning

The process of therapeutic agents moving across the natural lipid and protein barriers of the body, such as the skin or mucosal linings, to reach the systemic circulation or their target cells. This concept is fundamental to understanding how non-oral drug delivery systems, particularly those for hormones, achieve their clinical effect. Effective navigation determines the ultimate success of the compound in bypassing physiological checkpoints. This mechanism is critical in endocrinology for ensuring precise delivery of replacement hormones.