This refers to the complex, multi-level communication network within the human body, encompassing the precise transfer of signals between cells, tissues, and organ systems to coordinate life processes. It includes genetic instructions, hormonal signaling, neuronal impulses, and the cytokine-mediated communication of the immune system. Maintaining clear, efficient information flow is critical for homeostatic integrity and overall health.
Origin
The concept draws heavily from molecular biology and systems biology, originating with the “Central Dogma” of molecular biology—the flow of genetic information from DNA to RNA to protein. In the wellness domain, it expands to describe the holistic, integrated communication across the endocrine and nervous systems. This term emphasizes the communication aspect of physiology rather than just the components.
Mechanism
Key mechanisms involve receptor-ligand binding, where hormones and neurotransmitters act as signaling molecules, transmitting information across cell membranes to initiate intracellular cascades. Epigenetic modifications, which control gene expression without altering the DNA sequence, also play a vital role in regulating the flow of genetic instructions. Efficient biological information flow depends on the integrity of cell membranes and the proper synthesis and clearance of signaling molecules.
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