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Biological Information Fidelity

Meaning

Biological Information Fidelity describes the integrity and accuracy with which genetic, epigenetic, and cellular signaling information is transmitted, replicated, and interpreted throughout the organism. High fidelity means minimal error accumulation in DNA replication, precise epigenetic regulation, and clear, unambiguous cell-to-cell communication via hormones and cytokines. This is a core determinant of biological age and systemic health, as loss of fidelity contributes directly to cellular senescence and dysfunction.