Biological Entropy Mitigation refers to the proactive clinical and lifestyle strategies employed to counteract the natural tendency toward increasing disorder and loss of functional complexity within a biological system, which is a core feature of aging. The goal is to preserve cellular and systemic organization, thereby slowing the rate of biological decline and extending the period of robust health. This involves reducing cellular damage and enhancing repair mechanisms.
Origin
The term draws upon the physical concept of entropy—the measure of disorder—and applies it to the process of biological aging, viewing aging as an accumulation of molecular and cellular damage. This perspective shifts the focus of longevity science toward actively maintaining internal order and complexity, a hallmark of young, healthy systems. It provides a framework for understanding why cellular processes become less efficient over time.
Mechanism
Mitigation strategies target fundamental cellular processes that drive entropic decay, such as chronic inflammation, oxidative stress, and genomic instability. Hormonal health plays a central role, as declining levels of protective hormones like DHEA and growth hormone accelerate this disorder. By supporting mitochondrial function, enhancing proteostasis (protein turnover), and maintaining optimal endocrine signaling, the body’s capacity for self-repair and structural integrity is significantly preserved.
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