The application of precise, data-driven interventions to positively influence genetically predisposed physiological trajectories, particularly concerning endocrine health and longevity. It acknowledges inherent biological programming while asserting the capacity to modulate outcomes through targeted lifestyle and therapeutic strategies. This concept focuses on optimizing inherent potential.
Origin
This term merges concepts from modern genetics and personalized medicine, emphasizing the actionable aspects of genomic potential. It moves away from a fatalistic view of inherited health risks by focusing on epigenetic modification. The ‘control’ aspect refers to the practitioner’s ability to steer physiological expression.
Mechanism
Control is exerted primarily through modulating gene expression via nutritional biochemistry and hormone signaling modulation, rather than altering the germline DNA itself. For instance, optimizing methylation patterns can influence the expression of genes related to insulin responsiveness or androgen receptor sensitivity. Precision testing identifies the levers needed to override suboptimal default settings.
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