The comprehensive system of control exerted by the body’s internal timing mechanisms, particularly the master clock in the suprachiasmatic nucleus (SCN), over nearly all physiological and hormonal processes. This governance dictates the 24-hour (circadian) rhythms of sleep, hormone release, metabolism, and behavior. Maintaining strong biological clock governance is fundamental for optimal health and longevity.
Origin
This concept originates from the scientific field of chronobiology, where the term “biological clock” or “circadian clock” describes the intrinsic, approximately 24-hour oscillation of biological processes. The SCN is the central pacemaker, deriving its name from its location above the optic chiasm in the brain.
Mechanism
The SCN receives light input from the retina, which synchronizes the core clock genes (like Period and Cryptochrome) that drive the circadian cycle. This master clock then sends signals to peripheral clocks in organs like the liver and adrenals, coordinating the rhythmic release of hormones such as melatonin and cortisol. Effective governance ensures that hormone secretion patterns are precisely aligned with the external light-dark cycle.
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