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Biological Chronometer

Meaning

The Biological Chronometer is a conceptual and measurable representation of an individual’s physiological age and cumulative biological wear-and-tear, distinct from their chronological age. This internal timekeeper is a composite measure derived from analyzing various molecular markers, particularly epigenetic modifications like DNA methylation patterns, telomere length, and other biomarkers of cellular senescence. It provides a clinical metric for the pace of aging, reflecting the efficiency of cellular maintenance and repair processes over time. A younger biological chronometer relative to chronological age suggests greater longevity potential and enhanced health span.