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Biological Buffer Capacity

Meaning

Biological buffer capacity quantifies a physiological system’s intrinsic ability to resist significant changes in mathrmpH when an acid or base load is introduced. This essential homeostatic mechanism ensures that the concentration of hydrogen ions remains within the narrow, tightly controlled range necessary for enzymatic reactions and cellular functions to proceed correctly. In the context of hormonal health, maintaining this stable internal environment is paramount because the activity and stability of many peptide hormones and receptors are exquisitely mathrmpH-sensitive. A robust buffer capacity reflects a healthy, adaptable physiological state capable of managing metabolic byproducts.