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Biological Agitation

Meaning

Biological agitation describes a state of heightened physiological arousal characterized by increased sympathetic nervous system activity and dysregulated hormonal secretion. Clinically, this manifests as restlessness, anxiety, and a compromised capacity for homeostatic regulation. It often results from chronic exposure to perceived stressors, leading to sustained elevations in glucocorticoids like cortisol and catecholamines. This chronic neuroendocrine overdrive depletes adaptive reserves and predisposes the individual to metabolic and immune dysfunction.