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Biological Aging Pathways

Meaning

Biological Aging Pathways are the fundamental, interconnected molecular and cellular processes that progressively lead to the decline in physiological function, increased susceptibility to disease, and loss of homeostatic capacity over time. These pathways represent the quantifiable mechanisms, such as telomere attrition, mitochondrial dysfunction, and cellular senescence, that drive the discrepancy between chronological age and functional biological age. Understanding these pathways is central to longevity medicine and clinical intervention.