The controlled delivery or introduction of a biologically active substance like a hormone or therapeutic agent into a physiological system to achieve a targeted systemic or local effect. This process requires precise dosing and timing relative to the body’s existing homeostatic mechanisms. In endocrinology, this often relates to exogenous hormone replacement or modulation.
Origin
Derived from the combination of “biological,” relating to living organisms, and “administration,” meaning the management or application of something. Its clinical context is rooted in pharmacology and endocrinological treatment protocols. Understanding the route and rate of delivery is crucial for predicting endocrine response.
Mechanism
This involves the chosen route of entry which dictates the substance’s absorption, distribution, metabolism, and excretion. Proper administration ensures the agent reaches its target receptors, initiating the desired downstream signaling cascade or feedback loop within the endocrine axis. The goal is to mimic or correct endogenous hormone fluctuations effectively.
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