Biohacking Human Biology describes the intentional application of systems-based, often technology-driven, interventions to optimize human physiological performance, healthspan, and subjective well-being. This practice integrates data acquisition from wearables or labs with targeted lifestyle or pharmacological adjustments. We approach this from a perspective of precise, measurable modulation of biological systems, particularly endocrine and metabolic function.
Origin
The term merges “biology” with “hacking,” suggesting an engineering mindset applied to self-improvement outside of traditional medical frameworks. Its recent prominence reflects a growing desire for personal agency over inherent physiological baselines.
Mechanism
Optimization mechanisms often target feedback loops within the neuroendocrine system, such as improving insulin sensitivity or optimizing circadian rhythms through light exposure or temperature manipulation. Successful biohacking relies on iterative feedback based on objective biomarkers to refine inputs affecting cellular and systemic function.
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