The deliberate application of systems-level analysis and targeted interventions to optimize the efficiency and function of the gastrointestinal tract. This process involves precise dietary adjustments, strategic supplementation, and lifestyle modifications based on personalized physiological data. The objective is to maximize nutrient assimilation and support the integrity of the gut-hormone axis.
Origin
The concept stems from the broader “biohacking” movement, which applies a do-it-yourself biology approach to human performance and longevity, merged with clinical gastroenterology principles. It is fundamentally rooted in the recognition of the gut microbiome’s pivotal role in systemic health, endocrinology, and neuroendocrine signaling. This modern term reflects an empowered, data-driven approach to digestive wellness.
Mechanism
Interventions are designed to modulate the gut microbiota composition, optimize digestive enzyme secretion, and strengthen the intestinal barrier function. Improving gut integrity reduces systemic inflammation and minimizes the metabolic burden associated with dysbiosis. This optimization enhances the enteroendocrine system’s signaling, directly influencing metabolic hormones like insulin and leptin.
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