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Bioenergetic Throughput Maximization

Meaning

This refers to the clinical objective of optimizing the total rate at which the organism can process energy substrates, primarily through mitochondrial respiration and ATP production. Achieving maximization means ensuring that substrate availability aligns precisely with the cell’s capacity for oxidative phosphorylation. We aim to move the highest volume of metabolic fuel through the system efficiently without inducing oxidative stress or substrate backup. This metric reflects the functional efficiency of cellular energy currency generation.