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Bioenergetic Signaling Pathways

Meaning

The complex, interconnected molecular cascades within cells that regulate energy production, utilization, and sensing, primarily centered around mitochondrial function and the generation of Adenosine Triphosphate (ATP). These pathways, including AMP-activated protein kinase (AMPK) and Sirtuins, act as cellular energy sensors, coordinating metabolic responses with environmental and hormonal cues. Their proper function is essential for maintaining cellular homeostasis and supporting high-demand processes, such as neurological activity. Dysregulation in these pathways is implicated in numerous age-related and metabolic disorders.