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Bioenergetic Hormone Interplay

Meaning

Bioenergetic Hormone Interplay describes the complex, bidirectional communication and functional relationship between the endocrine system and the cellular processes governing energy production and utilization. This critical interaction involves hormones like insulin, thyroid hormone, cortisol, and testosterone directly regulating mitochondrial function, glucose uptake, and lipid metabolism within cells. The efficiency of this interplay dictates systemic energy balance, metabolic flexibility, and overall physiological resilience. Dysregulation in this axis often manifests as metabolic syndrome or chronic fatigue, underscoring its clinical significance.