Quantifiable data derived from the analysis of endogenous substances within biological matrices, such as blood, urine, or saliva. This information provides a snapshot of current physiological states, including substrate utilization, endocrine activity, and metabolic flux. Precise measurement is essential for understanding systemic health dynamics.
Origin
This term merges the foundational science of biochemistry—the study of chemical processes within living organisms—with the modern imperative of data acquisition. Its utility arises from translating molecular events into clinically actionable metrics. The historical foundation lies in developing reliable assays for hormones and metabolites.
Mechanism
Biochemical information operates by reflecting the output of cellular machinery interacting with the internal and external environment. For example, circulating insulin levels signal cellular response to nutrient load, reflecting the efficiency of the glucose disposal mechanism. Analysis of these biomarkers reveals deviations from homeostatic set points, guiding targeted therapeutic adjustments.
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