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Bioavailable T Titration

Meaning

Bioavailable T Titration is the precise, individualized clinical process of adjusting therapeutic Testosterone (T) dosages to achieve optimal circulating levels of the non-sex hormone-binding globulin (SHBG) bound fraction. This measurement represents the biologically active portion of the hormone, directly accessible to target tissues. The goal is to maintain the patient’s bioavailable testosterone within a clinically defined, high-normal reference range to maximize physiological benefit while mitigating potential side effects. This method ensures the therapeutic intervention is precisely matched to the individual’s needs.