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Bioavailability Vectoring

Meaning

Bioavailability Vectoring is a specialized pharmaceutical strategy focused on designing and engineering a delivery system to actively guide a therapeutic compound to its intended site of action within the body, thereby maximizing its systemic absorption and therapeutic concentration. This method specifically aims to overcome physiological barriers, such as first-pass hepatic metabolism or poor membrane permeability, which normally limit a compound’s effectiveness. By ‘vectoring’ the compound, clinicians achieve a predictable and optimized exposure profile at the target tissue, enhancing efficacy and minimizing required dosage.