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Bioactive Hormone Monitoring

Meaning

Bioactive Hormone Monitoring refers to the clinical measurement of the fraction of a hormone that is unbound to carrier proteins, thus being biologically available to exert its effect on target tissues. This contrasts with total hormone measurement, which includes both bound and unbound forms, providing an incomplete picture of tissue exposure. Assessing the free or bioavailable fraction provides a more accurate physiological assessment of hormonal status and functional activity. Precise monitoring is essential for optimizing hormone replacement therapy and accurately diagnosing subtle endocrine disorders.