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Bioactive Androgen Requirements

Meaning

This term defines the specific, necessary concentrations of unbound and readily available androgen hormones, primarily free testosterone and dihydrotestosterone, required at the tissue level for optimal physiological function. These requirements are distinct from total hormone levels, as they represent the fraction capable of binding to androgen receptors and exerting biological effects. Clinically, determining these requirements is crucial for accurately diagnosing and managing androgen deficiency in both males and females.