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Bio-System Resilience

Meaning

Bio-System Resilience is the inherent capacity of an organism’s interconnected physiological networks—including the neuroendocrine, metabolic, and immune systems—to resist, adapt to, and rapidly recover from internal or external stressors. This metric is more dynamic than simple homeostasis, representing the ability to maintain optimal function and prevent allostatic load when faced with challenges like chronic psychological stress or environmental toxins. High resilience is a key indicator of robust healthspan and longevity, suggesting a system that efficiently manages wear and tear. Clinically, resilience is assessed by observing the dynamic response of key biomarkers to controlled physiological challenges.