Bio-Signal Fidelity describes the accuracy and clarity with which biochemical information, such as a hormone’s concentration, is transmitted from its source to the target cell receptor without distortion or degradation. High fidelity implies that the signal received elicits the precise, intended cellular response. We assess this by examining receptor function and downstream signaling integrity.
Origin
This concept borrows precision from signal processing and telecommunications, applying the term ‘fidelity’ to measure the faithfulness of biological information transfer within the body’s chemical regulatory networks.
Mechanism
Signal fidelity is maintained through intact receptor structure, optimal ligand-binding kinetics, and an environment free from excessive oxidative stress or competing molecular noise. When fidelity is high, endocrine commands result in predictable, efficient gene expression changes necessary for homeostasis.
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