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Bio-Marker Temporal Alignment

Meaning

Bio-Marker Temporal Alignment refers to the clinical strategy of measuring multiple physiological indicators, or biomarkers, at precisely coordinated time points to accurately reflect their interconnected dynamics and inherent circadian rhythms. This precise timing is essential because the concentrations of many critical hormones, neurotransmitters, and metabolites fluctuate significantly throughout the 24-hour cycle. Proper temporal alignment provides a more accurate, contextualized snapshot of an individual’s dynamic hormonal and metabolic status, moving beyond single, potentially misleading static measurements.