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Bio-Individual Setpoint Determination

Meaning

Bio-Individual Setpoint Determination is the clinical process of identifying the optimal, homeostatic concentration range for specific physiological parameters, such as hormones, metabolites, or biomarkers, that is unique to a single patient. This concept moves beyond standard population reference ranges to define a personalized target zone that correlates directly with the patient’s reported well-being, peak functional capacity, and absence of symptoms. It acknowledges that genetic, lifestyle, and environmental factors mandate a unique clinical objective for each person.