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BDNF Signaling Pathways

Meaning

BDNF Signaling Pathways encompass the complex intracellular communication cascades initiated by Brain-Derived Neurotrophic Factor, a protein essential for neuronal survival, differentiation, and synaptic plasticity. This neurotrophin plays a pivotal role in maintaining cognitive health, mood regulation, and memory consolidation throughout the lifespan. Optimal function of these pathways is directly correlated with neurogenesis in the hippocampus, a process significantly influenced by endocrine factors like sex steroids and growth hormone.