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BCL-6 Protein

Meaning

BCL-6 protein, or B-cell lymphoma 6 protein, is a transcription factor critical for regulating gene expression within various cell types, particularly B-cells in the immune system. Its function as a transcriptional repressor is integral to germinal center formation and the differentiation of B-lymphocytes, which are central to adaptive immunity. Clinically, aberrant expression or function of BCL-6 is frequently associated with specific subtypes of lymphoma. In the context of hormonal health, its regulatory role in cellular proliferation and differentiation is a key point of interest for systemic health and disease pathways.