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Bcl-2/Bax Ratio

Meaning

The Bcl-2/Bax Ratio is a critical quantitative measure in cellular physiology that reflects the balance between anti-apoptotic and pro-apoptotic proteins. It is used as a molecular biomarker to predict a cell’s susceptibility to programmed cell death, known as apoptosis. A higher ratio typically favors cell survival, while a lower ratio signals an impending cellular demise, a process vital for tissue turnover and disease prevention. This ratio provides tangible insight into cellular resilience and longevity, a cornerstone of hormonal health.