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Baseline Obsolescence

Meaning

Baseline Obsolescence is a conceptual term in longevity medicine describing the progressive, detrimental shift of an individual’s fundamental physiological and hormonal set points over time. It signifies that the body’s homeostatic “normal” gradually declines with age or chronic stress, leading to a new, suboptimal functional state that the body incorrectly accepts as its current baseline. This phenomenon is a subtle yet pervasive driver of age-related decline, making the restoration of youthful function a matter of resetting the baseline.