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HRTioSeptember 30, 2025
Autoregulatory Reset
Meaning
Autoregulatory Reset refers to the clinical strategy of temporarily withdrawing an exogenous hormonal or signaling agent to allow the body’s intrinsic endocrine feedback mechanisms to re-establish their baseline sensitivity and function. This planned cessation is a critical intervention designed to reverse receptor downregulation and restore the hypothalamic-pituitary-target organ axis’s natural pulsatility and responsiveness. It is a necessary step to maintain long-term therapeutic efficacy and prevent iatrogenic dependence.
Provided by the clinical team
at 4Ever Young Miami Dadeland
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