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Autoimmune Disease Considerations

Meaning

Autoimmune disease considerations represent the essential clinical assessment and strategic planning required when initiating or managing hormonal therapies in individuals diagnosed with an autoimmune disorder, such as Hashimoto’s thyroiditis, Lupus, or Rheumatoid Arthritis. These considerations are vital because sex hormones, including estrogen, progesterone, and androgens, possess complex immunomodulatory properties that can either exacerbate or ameliorate the underlying inflammatory and immune dysregulation characteristic of these conditions. A thorough risk-benefit analysis must precede treatment, acknowledging the bidirectional relationship between the endocrine and immune systems.