The quantifiable efficiency and effectiveness of cognitive processes responsible for selective concentration, sustained focus, and the ability to shift mental resources appropriately. This neurocognitive function is deeply modulated by circulating hormones, including thyroid hormones and glucocorticoids like cortisol, which influence neuronal excitability and synaptic plasticity. Optimal attentional performance is crucial for executive function and is a sensitive indicator of central nervous system homeostasis, reflecting the overall hormonal milieu.
Origin
The concept combines the psychological term “attention,” derived from the Latin attendere (to stretch toward), with “performance,” referring to the execution of an action. In a clinical context, its application stems from neuropsychology and psychophysiology, where standardized tests are used to measure the quality of focus. Within endocrinology, its relevance emerged from observing the cognitive deficits associated with hormonal imbalances, such as hypo- or hyperthyroidism and chronic stress-induced cortisol dysregulation.
Mechanism
Hormones exert their influence on attention primarily through binding to nuclear and membrane receptors in brain regions critical for focus, such as the prefrontal cortex and hippocampus. Glucocorticoids regulate the stress response system, impacting alertness and distraction thresholds. Furthermore, sex hormones, like estrogen and testosterone, modulate neurotransmitter systems, including dopamine and norepinephrine, which are integral for maintaining vigilance and processing speed, thereby directly governing attentional performance.
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