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Atrogene Expression

Meaning

Atrogene expression refers to the molecular process involving the transcription of specific genes that initiate and accelerate the breakdown of skeletal muscle tissue, a core component of age-related muscle wasting known as sarcopenia. This is a crucial indicator of catabolic dominance within the body’s physiological state. Clinically, monitoring this genetic activity provides insight into the underlying mechanisms driving lean mass loss and functional decline. The process represents a fundamental shift in cellular balance toward protein degradation over synthesis.