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Atherogenic Particle Reduction

Meaning

Atherogenic particle reduction refers to the clinical strategy and measurable outcome of decreasing the concentration and modifying the composition of specific lipoprotein particles within the circulation that contribute to the formation of atherosclerotic plaque. This primary focus is often on lowering the number of small, dense low-density lipoprotein (sdLDL) particles and remnants, which are particularly prone to endothelial penetration and oxidation. Successfully achieving this reduction is a key objective in cardiovascular risk management and is intrinsically linked to metabolic and hormonal balance.