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Astrocyte Signaling

Meaning

Astrocyte signaling refers to the complex communication processes orchestrated by astrocytes, the most abundant glial cells in the central nervous system, which are crucial for maintaining brain homeostasis and modulating neuronal activity. These star-shaped cells actively participate in synaptic transmission, regulate the integrity of the blood-brain barrier, and manage the local cerebral environment. In the context of hormonal health, this signaling is paramount for proper neuroendocrine regulation, as astrocytes influence the activity of the hypothalamus and the pituitary gland, thereby impacting systemic hormone release and overall cognitive function.