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Aromatase Activity Markers

Meaning

Aromatase Activity Markers are biochemical indices utilized in clinical endocrinology to assess the functional capacity and rate of the aromatase enzyme, which converts androgens, primarily testosterone, into estrogens. These markers typically include the ratio of testosterone to estradiol (T:E2) and the direct measurement of estrogen metabolites in serum or urine. Elevated aromatase activity can lead to an undesirable increase in circulating estrogen and a corresponding decrease in functional androgen levels, particularly relevant in male hormonal health. Monitoring these markers is essential for managing hormone therapy and preventing potential side effects.