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ApoA-I Mimetics

Meaning

ApoA-I Mimetics are synthetically engineered peptides or small molecules specifically designed to replicate the biological functions of apolipoprotein A-I (ApoA-I), the primary protein constituent of high-density lipoprotein (HDL). These agents are developed to enhance the body’s capacity for reverse cholesterol transport, which is the process of removing excess cholesterol from peripheral cells. Their therapeutic potential is primarily focused on mitigating atherosclerosis and improving overall cardiovascular and metabolic health. Maintaining optimal lipid profiles is crucial for systemic longevity, especially as hormonal shifts occur with advancing age.