AOD-9604 Fat Loss refers to the use of AOD-9604, a synthetic peptide fragment of the human growth hormone (HGH) molecule, engineered to selectively mimic the lipolytic, or fat-breaking, effects of HGH. This peptide is designed to promote the reduction of adipose tissue mass without stimulating growth or adversely affecting insulin sensitivity. Clinical application focuses on its potential as a targeted pharmacological intervention within metabolic health strategies for localized fat reduction.
Origin
The peptide AOD-9604 was developed through extensive research aimed at isolating the specific region of the growth hormone molecule responsible for fat metabolism. Scientists sought to create a therapeutic agent that could harness the powerful fat-reducing properties of HGH without the associated side effects, such as elevated IGF-1 levels or glucose dysregulation. Its name is a laboratory designation reflecting its developmental sequence and structural composition.
Mechanism
AOD-9604 is thought to exert its primary effect by stimulating lipolysis and inhibiting lipogenesis, the breakdown and synthesis of fat, respectively. It specifically binds to a receptor on fat cells, triggering the release of stored fat from the cells for energy use and oxidation. Crucially, its mechanism of action is distinct from full-length HGH; it does not engage the GHR receptor pathway associated with growth promotion, making it a targeted tool for fat mobilization.
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