Antiaging nutrition protocols represent structured dietary and supplemental regimens clinically designed to modulate biochemical pathways associated with cellular aging and decline. These protocols are implemented to promote longevity and enhance healthspan by optimizing nutrient intake, managing systemic inflammation, and supporting hormonal balance. The focus extends beyond basic caloric needs to target specific molecular mechanisms of senescence and cellular repair.
Origin
This term is a modern clinical construct blending ‘antiaging’ concepts, which arose from gerontology and regenerative medicine, with ‘nutrition protocols,’ emphasizing a systematic, evidence-based approach to dietary intervention. It is a key component of functional and precision medicine in the wellness space. The underlying principle is that food acts as information for the genome.
Mechanism
The mechanism of action centers on influencing key nutrient-sensing pathways, notably mTOR, AMPK, and sirtuins, which regulate cellular metabolism and stress resistance. Protocols often leverage caloric restriction mimetics, specific micronutrient delivery, and phytonutrient compounds to enhance autophagy and DNA repair processes. By carefully controlling macronutrient ratios and timing, these diets aim to stabilize blood glucose and insulin levels, thereby reducing advanced glycation end-products and oxidative stress.
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