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Anti-TPO Antibodies

Meaning

Anti-TPO antibodies are specific autoantibodies directed against the thyroid peroxidase enzyme, a critical protein found in the thyroid gland. Their presence in the bloodstream is a primary serological marker for autoimmune thyroid disease, most commonly Hashimoto’s thyroiditis. These immunoglobulins signify an immune system error where the body mistakenly attacks its own thyroid tissue. Clinically, high titers suggest ongoing thyroid inflammation and potential future hypothyroidism.