Interventions employing specific biochemical agents designed to counteract cellular aging processes and promote longevity pathways at the molecular level. These strategies move beyond symptomatic management toward addressing fundamental drivers of biological decline. Such chemical modulation aims to preserve functional cellular machinery.
Origin
Rooted in gerontology and molecular biology, focusing on chemical modulation to delay the hallmarks of senescence, such as genomic instability and epigenetic alterations. The term implies a deliberate, targeted chemical approach to extending healthspan. It signifies a proactive stance against age-related functional decay.
Mechanism
These strategies often target mechanisms like telomere attrition, mitochondrial dysfunction, or the accumulation of senescent cells through specific pharmacological or supplemental agents. For example, modulating NAD+ precursors can influence sirtuin activity, a critical pathway in cellular maintenance. Effective implementation requires understanding receptor kinetics.
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