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Anti-Mineralocorticoid

Meaning

An anti-mineralocorticoid is a class of pharmacological agents that specifically antagonize the effects of mineralocorticoid hormones, primarily aldosterone, within the body. These compounds are frequently employed in clinical endocrinology to manage conditions characterized by excessive mineralocorticoid activity, such as primary hyperaldosteronism and certain forms of resistant hypertension. They play a vital role in regulating electrolyte balance, specifically influencing sodium and potassium levels, and maintaining fluid homeostasis. These agents help mitigate the detrimental effects of aldosterone on cardiovascular and renal tissues.