What is the Origin of Anti-Inflammaging Strategy?

This term merges "anti-inflammatory" concepts with the process of aging ("senescence"), framing age-related immune activation as a targetable condition. It originates from gerontology and translational medicine, where mitigating cumulative cellular damage is paramount. The strategy recognizes that persistent low-level cytokine release impairs hormonal responsiveness.

What is the Mechanism of Anti-Inflammaging Strategy?

Strategies often involve optimizing nutrient sensing pathways, modulating the inflammasome activity, or supporting mitochondrial health to reduce reactive oxygen species production. By dampening pro-inflammatory cytokine release, we aim to improve cellular signaling fidelity, particularly concerning insulin and steroid hormone action. This approach seeks to normalize the inflammatory milieu that otherwise accelerates physiological decline.

Anti-Inflammaging Strategy ∞ Area

Anti-Inflammaging Strategy

Meaning

An Anti-Inflammaging Strategy refers to targeted clinical or lifestyle interventions designed to counteract the chronic, low-grade, sterile inflammation that accumulates with age. This systemic inflammation, often termed “inflammaging,” is a significant driver of age-related cellular dysfunction and pathology. Our goal is to modulate inflammatory signaling pathways to preserve tissue integrity and endocrine function.