What is the Origin of Anti-Inflammaging Intervention?

This neologism is a blend of the prefix 'anti-' meaning 'against,' and the portmanteau 'inflammaging,' which was coined to describe the state of chronic, sterile inflammation that increases with chronological age. The concept emerged from gerontology and immunology research, recognizing inflammation as a central, modifiable component of the aging phenotype.

What is the Mechanism of Anti-Inflammaging Intervention?

Interventions operate by modulating key inflammatory pathways, such as the NF-κB cascade or the inflammasome, using pharmacological agents, targeted nutrients, or specific lifestyle changes. By reducing the persistent activation of innate immune cells, the systemic inflammatory burden is lowered. This tuning promotes cellular repair, improves tissue function, and decreases the risk profile for numerous age-associated pathologies.

Anti-Inflammaging Intervention ∞ Area

Anti-Inflammaging Intervention

Meaning

A targeted clinical or lifestyle strategy specifically designed to mitigate chronic, low-grade systemic inflammation, a process often termed “inflammaging,” which is a key driver of age-related decline and chronic disease. These interventions aim to rebalance the immune system and reduce the circulating levels of pro-inflammatory cytokines. Achieving this reduction is paramount for extending healthspan and improving overall physiological resilience.