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Anti-Glucocorticoid Effect

Meaning

The Anti-Glucocorticoid Effect describes the physiological or pharmacological action of a substance that counteracts or diminishes the effects of glucocorticoid hormones, such as cortisol, at their receptor sites. This mechanism is clinically important because it can mitigate the catabolic, immunosuppressive, and metabolic side effects associated with excessive cortisol activity or exogenous steroid use. Maintaining a healthy balance between glucocorticoids and their antagonists is vital for systemic homeostasis.