A broad spectrum of medical and wellness modalities specifically engineered to slow, halt, or reverse the detrimental biological processes associated with senescence and chronological aging. These therapeutic strategies are clinically applied with the intent of optimizing biological function, improving healthspan, and extending the period of high-quality life. Treatments move beyond superficial cosmetic changes to target the fundamental cellular and molecular hallmarks of aging.
Origin
This concept has roots in ancient philosophical quests for eternal youth, but its modern, scientific form is derived from the field of gerontology and the molecular biology of aging. The term emerged as research identified specific, modifiable pathways of senescence, transitioning the focus from simply accepting aging to actively intervening in its biological mechanisms. It represents the medicalization of longevity science.
Mechanism
The mechanism of action typically focuses on several core pathways of aging, including the clearance of senescent cells, the stabilization of telomere length, and the enhancement of mitochondrial bioenergetics. Specific treatments may utilize hormonal modulation to restore youthful endocrine signaling or employ metabolic compounds to improve cellular stress resistance. Ultimately, these interventions seek to restore optimal cellular repair and regeneration capacity across multiple organ systems.
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