Clinical substances or protocols aimed at mitigating the physiological manifestations of senescence, often targeting endocrine function decline. These agents seek to modulate cellular pathways implicated in age-related deterioration. Our focus remains on evidence-based approaches supporting vitality.
Origin
This terminology arises from the intersection of gerontology and endocrinology, reflecting a shift from merely treating age-related diseases to actively intervening in the aging process itself. The concept centers on restoring youthful physiological parameters.
Mechanism
Mechanisms typically involve optimizing receptor sensitivity, supporting mitochondrial function, or modulating anabolic hormone axes like the somatotropic system. Effective agents aim to re-establish endocrine homeostasis characteristic of younger biological states.
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