Clinical application of strategies to slow, halt, or partially reverse physiological aging processes, often focusing on molecular and endocrine markers. This involves assessing biomarkers to tailor interventions that support optimal cellular function and tissue integrity over time. We aim to extend healthspan alongside chronological years.
Origin
Derived from the convergence of gerontology and functional medicine, where ‘optimization’ implies moving beyond standard reference ranges toward peak physiological performance. The ‘anti-aging’ component addresses the progressive decline in homeostatic mechanisms seen with advancing age. This concept reframes aging from an inevitability to a modifiable process within the context of endocrine balance.
Mechanism
It frequently targets pathways like sirtuin activation, telomere maintenance, and mitigation of cellular senescence. Key actions involve modulating sex hormone levels, improving insulin sensitivity, and enhancing mitochondrial efficiency. Through these targeted adjustments, the goal is to restore a more youthful hormonal milieu, supporting anabolic processes and reducing chronic inflammation.
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